Phosphatidylinositol 3-Kinases

Phosphotransferases that catalyzes the conversion of 1-phosphatidylinositol to 1-phosphatidylinositol 3-phosphate. Many members of this enzyme class are involved in RECEPTOR MEDIATED SIGNAL TRANSDUCTION and regulation of vesicular transport with the cell. Phosphatidylinositol 3-Kinases have been classified both according to their substrate specificity and their mode of action within the cell.

Also Known As:

PI 3 Kinase; PI3 Kinase; PI 3-Kinase; PI-3K; PI3 Kinases; PI3-Kinase; Phosphoinositide 3 Kinases; Phosphoinositide 3-Hydroxykinase; PtdIns 3-Kinases; 3-Hydroxykinase, Phosphoinositide; Kinase, PI-3; Kinase, Phosphatidylinositol-3-OH; Kinases, PI3; Kinases, Phosphoinositide 3; Phosphatidylinositol 3 Kinases; Phosphatidylinositol 3 OH Kinase; Phosphoinositide 3 Hydroxykinase; PtdIns 3 Kinase; PtdIns 3 Kinases; PI-3 Kinase; Phosphatidylinositol-3-OH Kinase; PtdIns 3-Kinase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Phosphatidylinositol 3-Kinases: 1486
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Phosphatidylinositol 3-Kinases: 1486

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Disease

Drug/Important Bio-Agent (IBA)